Algometer
Algometer - Related Videos
09:03
Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management
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Cited by 1 •
2025
Recent developments in pain research highlight the potential of photoneuromodulation using green light-emitting diodes (GLED) as a non-pharmacological treatment. GLED modulates pain pathways, offering effective pain relief. This article aims to standardize and refine GLED exposure protocols, improving consistency across studies and advancing the clinical application of this therapy.
07:28
A Protocol of Manual Tests to Measure Sensation and Pain in Humans
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Cited by 23 •
2016
The goal of this procedure is to demonstrate a battery of quantitative techniques for sensory and pain measurement in humans. The equipment and techniques described are commonly found in pain clinics or are easy to obtain.
07:09
In Vivo Calcium Imaging of Neuronal Ensembles in the Intact Dorsal Root Ganglia of a Mouse
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2025
Source: Shannonhouse, J., et al.In Vivo Calcium Imaging of Neuronal Ensembles in Networks of Primary Sensory Neurons in Intact Dorsal Root Ganglia. J. Vis. Exp. (2023).The video demonstrates an in vivo calcium imaging technique to monitor neuronal activity in the dorsal root ganglia (DRG) of a transgenic mouse. DRG neurons express a calcium indicator that increases fluorescence intensity upon binding to calcium. Mechanical or thermal stimuli applied to a hind paw generate action potentials that...
07:12
Assessment of Sensory Thresholds in Dogs Using Mechanical and Hot Thermal Quantitative Sensory Testing
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Cited by 6 •
2021
This work describes a standard protocol for mechanical and hot thermal quantitative sensory testing to evaluate the somatosensory system in dogs. Sensory thresholds are measured using an electronic von Frey anesthesiometer, pressure algometer, and hot contact thermode.
09:07
In Vivo Calcium Imaging of Neuronal Ensembles in Networks of Primary Sensory Neurons in Intact Dorsal Root Ganglia
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Cited by 3 •
2023
This protocol describes the surgical exposure of the dorsal root ganglion (DRG) followed by GCaMP3 (genetically-encoded Ca2+ indicator; Green Fluorescent Protein-Calmodulin-M13 Protein 3) Ca2+ imaging of the neuronal ensembles using Pirt-GCaMP3 mice while applying a variety of stimuli to the ipsilateral hind paw.
FAQs
An algometer reading reflects both pressure sensitivity and the participant’s response process. Reporting, attention, and testing conditions can alter the point at which a sensation is signaled, so the value should be interpreted as a behavioral measure shaped by the testing context rather than as an isolated indicator independent of participant behavior.
Gradual force application helps identify the threshold at which a participant reports pain or discomfort, while the calibrated probe supports consistent measurement. Applying pressure progressively at a selected body site makes responses more reproducible and allows researchers to compare sensitivity across individuals or across repeated assessments under defined conditions.
Pressure pain sensitivity provides a quantifiable behavioral outcome based on a participant’s reported sensation. Researchers can use differences in threshold values to examine sensory responses among individuals, relate behavioral responses to injury or disease, and evaluate whether treatment is associated with a change in pain-related behavior.
A typical procedure selects and identifies a body site, uses a calibrated probe, and increases pressure gradually while the participant attends to the sensation. The participant signals when pain or discomfort reaches the relevant threshold, and the resulting measurement can then be recorded for comparison across participants, sites, or testing sessions.
Reliability improves when researchers keep the testing procedure consistent and explain the participant’s task clearly. Standardized body-site selection, pressure application, and communication help reduce variation caused by differing conditions or misunderstandings. These controls are especially important because attention and reporting influence when participants signal their threshold.
Algometry is useful when a study needs a reproducible behavioral measure of pressure sensitivity. Researchers can compare responses between individuals, assess changes associated with injury or disease, or examine outcomes after treatment. Interpreting changes requires attention to the testing conditions and participant communication used at each assessment.