Cannula Manufacturing

Cannula manufacturing is the controlled production of hollow, precision-tubed devices that provide access for fluid delivery, sampling, or instrument placement, making it important in biomedical and behavioral research. The process typically shapes biocompatible materials into tubes with defined lumen dimensions, wall thickness, length, and tip geometry, then assembles and finishes components to support accurate placement and reliable flow. In behavioral neuroscience, manufactured cannulas can enable chronic administration of drugs or other solutions into targeted regions of animal models while minimizing repeated handling. Consistent dimensions and surface quality improve procedural reproducibility, experimental control, and interpretation of behavior-related outcomes.

Cannula Manufacturing - Related Videos

Research

JoVE EoE - Neurotherapeutics

Cannula Implantation into the Cisterna Magna in a Mouse Model

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2025

Source: Xavier, A. L. R., et al. Cannula Implantation into the Cisterna Magna of Rodents. J. Vis. Exp. (2018)This video demonstrates the procedure for implanting a cannula into the cisterna magna of an anesthetized mouse. The technique involves guiding a needle-mounted cannula through the dura into the inverted triangular cisterna magna and securing it for targeted delivery into the cerebrospinal fluid.

Research

JoVE Journal - Neuroscience

Direct Cannula Implantation in the Cisterna Magna of Pigs

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Cited by 1 •

2021

This article presents a step-by-step protocol for the direct cannula implantation in the cisterna magna of pigs.

Education

JoVE Core - Medical-Surgical Nursing

Administering Oxygen by Nasal Cannula

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2025

Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations. Nasal Cannulas A nasal cannula is a lightweight tube split into two prongs placed in the nostrils, connected...

Tracheal Cannulation in Rabbit Model: A Procedure to Insert Tracheal Cannula into the Rabbit Trachea

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2025

This video demonstrates the surgical creation of an opening in the rabbit trachea to insert a tracheal cannula for artificially ventilating the lungs.

Research

JoVE Journal - Cancer Research
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Intracranial Cannula Implantation for Serial Locoregional Chimeric Antigen Receptor (CAR) T Cell Infusions in Mice

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Cited by 8 •

2023

Central nervous system (CNS) tumors are the leading cause of cancer-related death in children, and locoregional immune-based therapies are increasingly being tested for patients in clinical trials. This protocol describes methods for locoregional cannula implantation in mice for the preclinical evaluation of immunotherapeutic infusions targeting CNS tumors.

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