Open-source Robot

An open-source robot is a programmable machine whose hardware designs, software, and documentation are openly available for inspection, modification, and sharing. It operates through coordinated control software, electronic components, sensors, and actuators that translate user-defined instructions into repeatable physical actions. In biochemistry, open-source robots can automate tasks such as liquid handling, sample preparation, reagent dispensing, and instrument control, helping researchers standardize experiments while reducing costs. Their adaptable designs support teaching, rapid prototyping, and collaborative method development, although reliable performance still depends on careful calibration, contamination control, and validation against established laboratory procedures.

Open-source Robot - Related Videos

Research

JoVE Journal - Neuroscience

Building An Open-source Robotic Stereotaxic Instrument

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Cited by 18 •

2013

This protocol includes the designs and software necessary to upgrade an existing stereotaxic instrument to a robotic (computer numeric controlled; CNC) stereotaxic instrument for around $1,000 (excluding a drill).

Research

JoVE Journal - Biochemistry

Shotgun Proteomics Sample Processing Automated by an Open-Source Lab Robot

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Cited by 8 •

2021

Detailed protocol and three Python scripts are provided for operating an open-source robotic liquid handling system to perform semi-automated protein sample preparation for mass spectrometry experiments, covering detergent removal, protein digestion, and peptide desalting steps.

Robotics in Surgery: A Modular Robotic Platform Driven Gastric Wedge Resection

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2025

Robotically assisted surgery has become highly popular in recent years. Presented here is the standard care for upper gastrointestinal procedures, including a demonstration of a robotic-assisted gastric wedge resection using a modular robotic device.

Research

JoVE Journal - Immunology and Infection
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Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots

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Cited by 15 •

2022

The protocol describes a SARS-CoV-2 diagnostic method that utilizes open-source automation to perform RT-qPCR molecular testing of saliva samples. This scalable approach can be applied to clinical public health surveillance as well as to increase the capacity of smaller university laboratories.

Insect-controlled Robot: A Mobile Robot Platform to Evaluate the Odor-tracking Capability of an Insect

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Cited by 18 •

2016

The capability to localize an odor source is necessary for insect survival and is expected to be applicable to artificial odor-tracking. The insect-controlled robot is driven by an actual silkmoth and enables us to evaluate the odor-tracking capability of insects through a robotic platform.

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