Bio-polymer Interface
Bio-polymer Interface - Related Videos
16:38
Bridging the Bio-Electronic Interface with Biofabrication
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Cited by 3 •
2012
This article describes a biofabrication approach: deposition of stimuli-responsive polysaccharides in the presence of biased electrodes to create biocompatible films which can be functionalized with cells or proteins. We demonstrate a bench-top strategy for the generation of the films as well as their basic uses for creating interactive biofunctionalized surfaces for lab-on-a-chip applications.
09:28
Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes
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Cited by 15 •
2017
We present a protocol for engineering the corona phase of near infrared fluorescent single walled carbon nanotubes (SWNTs) using amphiphilic polymers and DNA to develop sensors for molecular targets without known recognition elements.
08:12
Depolymerizable Olefinic Polymers Based on Fused-Ring Cyclooctene Monomers
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2022
Here, we describe protocols for the preparation of trans-cyclobutane fused cyclooctenes (tCBCO), their polymerization to prepare depolymerizable olefinic polymers, and the depolymerization of these polymers under mild conditions. Additionally, protocols for the preparation of depolymerizable networks and compression molding of rigid linear plastics based on this system are described.
09:09
Layer-by-layer Synthesis and Transfer of Freestanding Conjugated Microporous Polymer Nanomembranes
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Cited by 3 •
2015
In this paper we describe the interfacial synthesis of conjugated microporous polymers (CMP) on sacrificial substrates, and the dissolution of the substrate for the preparation of freestanding CMP nanomembranes. In addition, we will describe how the fragile nanomembranes can be transferred to other substrates.
16:24
Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
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Cited by 13 •
2012
The goal of this experiment is to determine and control the size, shape and stability of self-assembled discotic amphiphiles in water. For aqueous based supramolecular polymers such level of control is very difficult. We apply a strategy using both repulsive and attractive interactions. The experimental techniques applied to characterize this system are broadly applicable.
FAQs
Different interactions produce different forms of interfacial organization. Hydrogen bonding and electrostatic attraction can promote adhesion, while covalent coupling creates a stronger chemical connection between components. Adsorption allows molecules to accumulate at the boundary without requiring permanent bonding. Together, these interactions influence whether materials remain attached, how fluids contact the surface, and how molecules move across it.
Wettability describes how readily a surface interacts with a fluid, while swelling reflects changes in polymer volume after fluid uptake. Both properties can alter molecular transport across the boundary. Because transport affects molecular exchange between connected materials or tissues, controlling these characteristics helps engineers tune how an interface functions within drug-delivery systems, scaffolds, and other bioengineered devices.
Degradation can change the physical and chemical conditions at the boundary as the polymer breaks down. Those changes may affect adhesion, swelling, wettability, and molecular exchange, which in turn influence the behavior of the combined system. Considering degradation is therefore important when designing interfaces intended to maintain biocompatibility, mechanical integration, or device performance over an extended period.
Researchers should match the interfacial properties to the function required by the system. Adhesion and mechanical integration matter when a material must remain connected to tissue, whereas transport and molecular exchange are central to drug delivery and biosensing. Wettability, swelling, degradation, and the selected molecular interactions provide the main design variables for adjusting how the interface performs.
In tissue-engineering scaffolds, the interface helps determine how the scaffold interacts with living tissue and surrounding fluids. Interfacial adhesion and mechanical integration can support a stable connection, while wettability, swelling, and molecular transport influence exchange at the boundary. Controlling these characteristics can help engineers design scaffolds with behavior better suited to their intended biological environment.
For drug-delivery systems, interfacial transport and molecular exchange help determine how substances move between the polymer and its surroundings. In biosensors, interactions at the boundary influence how the material engages with the relevant biological environment. Adsorption, electrostatic attraction, hydrogen bonding, and covalent coupling offer different ways to adjust these interactions and the resulting system behavior.
An implant coating must function at the boundary between a material and living tissue, so its interfacial behavior can affect biocompatibility and mechanical integration. Adhesion helps the coating remain associated with the underlying system, while wettability, swelling, degradation, and molecular exchange influence longer-term performance. Designing these properties together supports more reliable interaction between the implant and its biological surroundings.