Solid Particle Encapsulation
Solid Particle Encapsulation - Related Videos
09:27
Encapsulation and Permeability Characteristics of Plasma Polymerized Hollow Particles
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Cited by 1 •
2012
We have used plasma enhanced chemical vapor deposition to deposit thin films ranging from a few nm to several 100 nm on nano-sized particles of various materials. We subsequently etch the core material to produce hollow nanoshells whose permeability is controlled by the thickness of the shell. We characterize the permeability of these coatings to small solutes and demonstrate that these barriers can provide sustained release of the core material over several days.
07:42
Green Synthesis, Characterization, Encapsulation, and Measurement of the Release Potential of Novel Alkali Lignin Micro-/Submicron Particles
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Cited by 4 •
2024
We describe novel, simple methodologies of synthesis and characterization of biocompatible lignin micro- and submicron particles. These formulations provide a facile approach for the utilization of the heteropolymer, as well as an alternative for the rational design of multifunctional carrier matrices with potential applicability in biomedicine, pharmaceutical technology, and the food industry.
07:44
Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen
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Cited by 2 •
2023
This method describes the encapsulation of the rabies antigen into biodegradable polymeric microparticles with structural and material properties that enable pulsatile release after a predetermined delay. Enzyme-linked immunosorbent assay (ELISA) assessment of the antigen retrieved from the particle core confirms the presence of intact trimeric rabies virus glycoprotein through particle fabrication.
04:42
Bacterial Cellulose Spheres that Encapsulate Solid Materials
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Cited by 1 •
2021
This protocol presents an easy, inexpensive method of forming bacterial cellulose (BC) spheres. This biomaterial can function as an encapsulation medium for solid materials, including biochar, polymer spheres, and mine waste.
16:19
High Throughput Single-cell and Multiple-cell Micro-encapsulation
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Cited by 17 •
2012
Combining monodisperse drop generation with inertial ordering of cells and particles, we describe a method to encapsulate a desired number of cells or particles in a single drop at kHz rates. We demonstrate efficiencies twice exceeding those of unordered encapsulation for single- and double-particle drops.
FAQs
Shell thickness helps determine how the encapsulated particles respond at their surfaces and how readily a contained active ingredient can be released. Engineering teams adjust thickness to balance protection against environmental exposure with the desired release behavior. Consistent thickness also supports more predictable particle performance, making thickness control important when reliability and repeatable processing outcomes are required.
Several processing routes can deposit the coating around solid cores. Fluidization and spraying apply coating material while particles are handled as separate units, whereas solvent removal or melt solidification forms the shell as the coating material changes state. The selected mechanism affects how the coating is deposited and which processing conditions must be controlled during shell formation.
These variables influence whether the coating forms a continuous shell and whether the resulting particles achieve consistent surface and release properties. Particle size affects the units being coated, while moisture and temperature influence processing conditions. Coating thickness directly contributes to protection and delivery behavior, so coordinated control helps limit variability in the final particle product.
A typical workflow begins by selecting the solid core and coating material, then choosing a suitable deposition route such as fluidization, spraying, solvent removal, or melt solidification. The process deposits coating around individual particles while operators manage particle size, moisture, temperature, and thickness. Processing continues until a continuous shell with the intended functional properties is formed.
The approach is useful when a product requires improved handling, stability, dispersibility, or resistance to environmental exposure. It also supports controlled delivery of active ingredients. These capabilities make the technology relevant to pharmaceutical and food processing, as well as agriculture, catalysis, and advanced materials, where particle behavior can influence product reliability and manufacturing efficiency.
Encapsulated particles can be engineered for controlled surface behavior and release, while also improving practical characteristics such as handling and dispersibility. In pharmaceuticals, food processing, and agriculture, these features can support delivery of active ingredients. In catalysis and advanced materials, tailored particle performance can contribute to more reliable products and more efficient manufacturing processes.