Toggle Vise

A toggle vise is a mechanical workholding device that secures a workpiece quickly and consistently, making it valuable for accurate and efficient engineering operations. It uses a hinged linkage that moves past its center position; when closed, the over-center toggle resists opening and converts applied motion into clamping force, while releasing the handle disengages the workpiece. Toggle vises support repetitive tasks such as machining, drilling, assembly, and welding by improving stability, reducing setup time, and helping maintain consistent part positioning. Their simple mechanism also makes them useful for studying force transmission, mechanical advantage, and fixture design.

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Research

JoVE Journal - Biology

Custom Smartphone Application to Guide Locomotor-Respiratory Coupling in the Field Using Step-Adaptive Breathing Sounds

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Cited by 3 •

2024

Locomotor-respiratory coupling (LRC) is potentially advantageous for runners but may be difficult to perform. We introduce a custom solution implemented on a smartphone to individualize and guide runners toward LRC.

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

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Cited by 46 •

2016

We present a protocol on how to utilize high-throughput cryo-electron tomography to determine high resolution in situ structures of molecular machines. The protocol permits large amounts of data to be processed, avoids common bottlenecks and reduces resource downtime, allowing the user to focus on important biological questions.

Fabrication of Bi2Te3 and Sb2Te3 Thermoelectric Thin Films using Radio Frequency Magnetron Sputtering Technique

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Cited by 3 •

2024

The manuscript describes a protocol for radio frequency magnetron sputtering of Bi2Te3 and Sb2Te3 thermoelectric thin films on glass substrates, which represents a reliable deposition method that provides a wide range of applications with the potential for further development.

Induction of Mild Traumatic Brain Injury in a Mouse Model

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2025

Source: Macheda, T., et. al. Electromagnetic Controlled Closed-Head Model of Mild Traumatic Brain Injury in Mice. J. Vis. Exp. (2022)This video demonstrates the procedure to induce a closed-head injury in a mouse model using a stereotaxic frame. The controlled impact replicates mild traumatic brain injury, allowing researchers to study neurological effects and recovery by measuring post-injury reflexes and behavior.

Analyzing Dendritic Morphology in Columns and Layers

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2017

Here, we show how to analyze dendritic routing of Drosophila medulla neurons in columns and layers. The workflow includes a dual-view imaging technique to improve the image quality and computational tools for tracing, registering dendritic arbors to the reference column array and for analyzing the dendritic structures in 3D space.

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