Unit Step Function

The unit step function is a mathematical model of an abrupt change, representing a signal that switches from zero to one at a specified time and providing a foundation for describing time-dependent systems in engineering. Defined as u(t)=0 for t<0 and u(t)=1 for t≥0, it can be shifted to u(t−a) to model activation at time a; multiplying it by an amplitude scales the change. Engineers use unit step functions to construct piecewise inputs, analyze transient responses in circuits and control systems, and apply convolution to determine the output of linear time-invariant systems, making them valuable for system modeling, simulation, and response prediction.

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Research

JoVE Journal - Medicine
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Monitoring Lung Function with Electrical Impedance Tomography in the Intensive Care Unit

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Cited by 6 •

2024

Electrical Impedance Tomography is a non-invasive, radiation-free, real-time pulmonary ventilation monitoring tool. By measuring impedance changes in the thorax, it can visualize the distribution of air on a breath-by-breath basis. Initially intended for ventilation monitoring, electrical impedance tomography can also measure perfusion via intravenous injection of a saline solution.

Generation of Human Motor Units with Functional Neuromuscular Junctions in Microfluidic Devices

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Cited by 12 •

2021

We describe a method to generate human motor units in commercially available microfluidic devices by co-culturing human induced pluripotent stem cell-derived motor neurons with human primary mesoangioblast-derived myotubes resulting in the formation of functionally active neuromuscular junctions.

Research

JoVE Journal - Chemistry

Preparation of a Corannulene-functionalized Hexahelicene by Copper(I)-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

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Cited by 1 •

2016

Here, we present a protocol to synthesize a complex organic compound comprised of three nonplanar polyaromatic units, assembled easily with reasonable yields.

A Functional Motor Unit in the Culture Dish: Co-culture of Spinal Cord Explants and Muscle Cells

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Cited by 16 •

2012

Cultured muscle cells are an inadequate model to recapitulate innervated muscle in vivo. A functional motor unit can be reproduced in vitro by innervation of differentiated human primary muscle cells using rat embryo spinal cord explants. This article describes how co-cultures of spinal cord explants and muscle cells are established.

Education

JoVE Core - Chemistry

Measurement: Standard Units

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2020

Every measurement provides three kinds of information: the size or magnitude of the measurement (a number), a standard of comparison for the measurement (a unit), and an indication of the uncertainty of the measurement. While the number and unit are explicitly represented when a quantity is written, the uncertainty is an aspect of the errors in the measurement results. The number in the measurement can be represented in different ways, including decimal form and scientific notation, which is...

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