Human-structure Interaction

Human-structure interaction is the study of how people and physical structures influence one another through forces, motion, and deformation. In physics, a person’s mass, movement, contact forces, and vibration can alter a structure’s response, while the structure’s stiffness, geometry, and dynamic behavior affect human stability, comfort, and perception. Researchers analyze this coupled system using mechanics, structural dynamics, measurements, and computational models. The topic informs the design of bridges, floors, buildings, vehicles, sports equipment, and assistive technologies, helping engineers predict resonance, reduce unwanted vibrations, improve safety, and create structures that respond effectively to human use.

Human-structure Interaction - Related Videos

Research

JoVE Journal - Bioengineering

Correlative Microscopy for 3D Structural Analysis of Dynamic Interactions

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Cited by 15 •

2013

We describe a correlative microscopy method that combines high-speed 3D live-cell fluorescent light microscopy and high-resolution cryo-electron tomography. We demonstrate the capability of the correlative method by imaging dynamic, small HIV-1 particles interacting with host HeLa cells.

Research

JoVE Journal - Chemistry
Free Sample

Mass Spectrometric Approaches to Study Protein Structure and Interactions in Lyophilized Powders

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Cited by 18 •

2015

Here, we present detailed protocols for solid-state amide hydrogen/deuterium exchange mass spectrometry (ssHDX-MS) and solid-state photolytic labeling mass spectrometry (ssPL-MS) for proteins in solid powders. The methods provide high-resolution information on protein conformation and interactions in the amorphous solid-state, which may be useful in formulation design.

Modeling Human Cerebellar Development In Vitro in 2D Structure

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Cited by 5 •

2022

The present protocol explains the generation of a 2D monolayer of cerebellar cells from induced pluripotent stem cells for investigating the early stages of cerebellar development.

High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem

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Cited by 5 •

2015

Here we present a protocol to determine the minimum number images that needed to be registered and averaged to resolve subcortical structures and test whether the individual layers of the LGN could be resolved in the absence of physiological noise.

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

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Cited by 4 •

2022

There is a need to determine which atherosclerotic lesions will progress in the coronary vasculature to guide intervention before myocardial infarction occurs. This article outlines the biomechanical modeling of arteries from Optical Coherence Tomography using fluid-structure interaction techniques in a commercial finite element solver to help predict this progression.

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