Thomas C. Irving

Thomas C. Irving

BioCAT, Illinois Institute of Technology

Affiliated withIllinois Institute of Technology

Research Area

Biography

Thomas Irving is Professor of Biology and Physics in the Department of Biological Sciences at the Illinois Institute of Technology in Chicago, Illinois. He received his B.Sc., M.Sc, and Ph.D. degrees from the University of Guelph, Ontario Canada.

He began his career studying muscle structure and function using small-angle X-ray diffraction of muscle as an undergraduate, continuing in his graduate studies. After a brief detour into cell biology at the University of Texas at Austin, he returned to X-ray diffraction as a staff scientist at the Cornell High Energy Synchrotron Source (CHESS), Ithaca NY. Here he received training in using synchrotron radiation for biophysical studies and worked with well-known muscle researchers including the late Hugh Huxley (Brandeis) and Michael Reedy (Duke University) on muscle diffraction studies.

In 1994 he moved to the Illinois Institute of Technology in Chicago to help launch the Biophysics Collaborative Access Team (BioCAT) project. BioCAT is organized as a NIH–supported Biotechnology Research Resource dedicated to structural studies of non-crystalline biological materials using Small and Wide-angle Fiber Diffraction and Macromolecular Small-Angle X-ray Scattering (SAXS) with emphasis on time and spatially resolved applications. The heart of the facility is Beamline 18ID, located on Sector 18 at the Advanced Photon Source (APS), Argonne National Laboratory in Argonne, IL. Professor Irving has been the Director of BioCAT and Principal Investigator of the P41 grant that funds it since 2001. He works with a number of investigator groups around the country and internationally to study the structure and function of muscle sarcomeric proteins especially in relation to muscle regulation.

JoVE Journal Publications

ArticleTotal : 1
Year
X-ray Diffraction of Intact Murine Skeletal Muscle as a Tool for Studying the Structural Basis of Muscle Disease
Publication title

Cited by 20

2019

Other Publications

Article
Year

Journal of cellular biochemistry| PubMed ID: 19530227

2009

Biophysical journal| PubMed ID: 12885653

2003

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16751282

2006

Biophysical journal| PubMed ID: 17293398

2007

Biophysical journal| PubMed ID: 18515368

2008

Journal of virology| PubMed ID: 18667514

2008

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 18669664

2008

Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment| PubMed ID: 18997878

2007

Journal of synchrotron radiation| PubMed ID: 19096178

2009

Biophysical journal| PubMed ID: 19450484

2009

Journal of structural biology| PubMed ID: 19635572

2009

Journal of molecular and cellular cardiology| PubMed ID: 20053351

2010

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21148419

2011

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 21368178

2011

American journal of physiology. Heart and circulatory physiology| PubMed ID: 21460195

2011

Biophysical journal| PubMed ID: 21463587

2011

American journal of physiology. Cell physiology| PubMed ID: 21593450

2011

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 21885653

2011

Biophysical journal| PubMed ID: 21961592

2011

Journal of molecular and cellular cardiology| PubMed ID: 22850286

2012

Biophysical journal| PubMed ID: 22995500

2012

Archives of biochemistry and biophysics| PubMed ID: 23246787

2013

PloS one| PubMed ID: 23285033

2012

Proceedings. Biological sciences / The Royal Society| PubMed ID: 23843386

2013

Biopolymers| PubMed ID: 23868289

2013

Journal of synchrotron radiation| PubMed ID: 24121320

2013

Journal of physics. Conference series| PubMed ID: 24489595

2013

Journal of molecular biology| PubMed ID: 24607691

2014

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 25002512

2014

Biophysical journal| PubMed ID: 25296301

2014

Archives of biochemistry and biophysics| PubMed ID: 25602701

2015

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 26124132

2015

Journal of applied crystallography| PubMed ID: 26306089

2015

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 26858417

2016

Journal of applied crystallography| PubMed ID: 27275136

2016

Molecular and cellular biochemistry| PubMed ID: 27520666

2004

The Journal of general physiology| PubMed ID: 27864330

2016

Journal of applied crystallography| PubMed ID: 27980506

2016

Cardiovascular research| PubMed ID: 28371863

2017

Structure (London, England : 1993)| PubMed ID: 29276036

2018

Annals of neurology| PubMed ID: 29328520

2018

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 29463717

2018

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 30104387

2018

Journal of molecular and cellular cardiology| PubMed ID: 30138628

2018

International journal of molecular sciences| PubMed ID: 30200618

2018

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 30249654

2018

Biophysical journal| PubMed ID: 30266320

2018

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 30365366

2019

The Journal of general physiology| PubMed ID: 30792184

2019

Biophysical journal| PubMed ID: 30850114

2019

The Journal of general physiology| PubMed ID: 30948421

2019

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 31110001

2019