Sinusoidal Harmonic Acceleration

Sinusoidal harmonic acceleration is a periodic acceleration that varies smoothly according to a sine wave, providing a controlled way to generate repeated mechanical motion or force. Its waveform is defined by acceleration amplitude, frequency, and phase, with the direction and magnitude changing continuously over time; integrating the signal describes the corresponding velocity and displacement. In behavioral research, this controlled stimulus can be used to examine how organisms detect, process, and respond to vibration, movement, or other mechanical perturbations. Standardized acceleration profiles also support comparisons across experiments and help link stimulus properties to behavioral performance, sensory sensitivity, and motor control.

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Education

JoVE Science Education - Physics

Hooke's Law and Simple Harmonic Motion

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2023

Source: Ketron Mitchell-Wynne, PhD, Asantha Cooray, PhD, Department of Physics & Astronomy, School of Physical Sciences, University of California, Irvine, CA Potential energy is an important concept in physics. Potential energy is the energy associated with forces that depend upon the position of an object relative to its surroundings. Gravitational potential energy, which is discussed in another video, is the energy associated that is directly proportional to the height of an object above...

Research

JoVE Journal - Bioengineering

Harmonic Nanoparticles for Regenerative Research

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2014

Protocol details are provided for in vitro labeling human embryonic stem cells with second harmonic generating nanoparticles. Methodologies for hESC investigation by multi-photon microscopy and their differentiation into cardiac clusters are also presented.

Harmonic Mean

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2023

The arithmetic mean is usually skewed towards the larger values in the data set. Therefore, to avoid this inherent bias towards smaller values, the harmonic mean is used. Take the example of the speed of a car, which is the measure of the rate of distance traveled. If the vehicle traverses the same distance back-and-forth, its average speed equals the total distance traveled divided by the total time taken. However, if the car moves with varying speeds, then the arithmetic mean is more skewed...

Force and Acceleration

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2023

Source: Nicholas Timmons, Asantha Cooray, PhD, Department of Physics & Astronomy, School of Physical Sciences, University of California, Irvine, CA The goal of this experiment is to understand the components of force and their relation to motion through the use of Newton's second law by measuring the acceleration of a glider being acted upon by a force. Nearly every aspect of motion in everyday life can be described using Isaac Newton's three laws of motion. They describe how objects in...

Research

JoVE Journal - Bioengineering

Simultaneous Label-Free Autofluorescence Multi-Harmonic Microscopy

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Cited by 6 •

2025

This protocol presents a step-by-step guide for the Simultaneous Label-free Autofluorescence Multi-harmonic (SLAM) microscopic technique, including details on how to generate the laser light source, prepare a tissue sample, conduct imaging, and analyze the data. SLAM advances nonlinear microscopy by measuring four complementary label-free contrasts to investigate the tissue microenvironment.

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