Single Dopant Dynamics

Single Dopant Dynamics examines how an individual impurity atom behaves within a semiconductor or other engineered material, where its discrete charge and energy states can strongly influence device performance. Local electric fields, thermal energy, and interactions with nearby carriers govern dopant ionization, charge capture and release, and transitions between electronic states. Measuring these processes reveals how nanoscale disorder affects conductivity, switching, and quantum behavior. In engineering, single-dopant studies support the design of ultrasensitive sensors, atomic-scale transistors, quantum devices, and more reliable semiconductor technologies by linking individual atomic events to measurable device characteristics.

Single Dopant Dynamics - Related Videos

Research

JoVE Journal - Engineering

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

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Cited by 3 •

2018

We demonstrate an all-electronic method to observe nanosecond-resolved charge dynamics of dopant atoms in silicon with a scanning tunneling microscope.

Research

JoVE Journal - Biochemistry

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET

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Cited by 2 •

2022

This study presents a detailed procedure to perform single-molecule fluorescence resonance energy transfer (smFRET) experiments on G protein-coupled receptors (GPCRs) using site-specific labeling via unnatural amino acid (UAA) incorporation. The protocol provides a step-by-step guide for smFRET sample preparation, experiments, and data analysis.

Research

JoVE Journal - Engineering
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Monitoring Conformational Dynamics of Single Unmodified Proteins using Plasmonic Nanotweezers

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Cited by 4 •

2025

Plasmonic nanotweezers use localized surface plasmon resonance in gold nanostructures to trap single nanoparticles, including proteins, within a nanometer-scale optical field. Changes in the scattered signal reveal protein presence and conformational dynamics, enabling monitoring without fluorophore modifications or surface tethering.

Studying Muscle Transcriptional Dynamics at Single-molecule Scales in Drosophila

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Cited by 3 •

2023

Drosophila is a well-established model for studying key molecules that regulate myogenesis. However, current methods are insufficient to determine mRNA transcriptional dynamics and spatial distribution within syncytia. To address this limitation, we optimized an RNA fluorescence in situ hybridization method allowing the detection and quantification of mRNAs at a single-molecule scale.

Single-Molecule Measurement of Protein Interaction Dynamics Within Biomolecular Condensates

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Cited by 7 •

2024

Many intrinsically disordered proteins have been shown to participate in the formation of highly dynamic biomolecular condensates, a behavior important for numerous cellular processes. Here, we present a single-molecule imaging-based method for quantifying the dynamics by which proteins interact with each other in biomolecular condensates in live cells.

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