Flexibility Method

The flexibility method is an analytical technique for solving statically indeterminate structures by determining unknown redundant forces from deformation compatibility. It first releases selected redundants to create a statically determinate primary structure, calculates the resulting displacements from applied loads and unit forces, and then enforces compatibility conditions so that the original supports or connections undergo their required movements. Using flexibility coefficients, the method relates forces to displacements through material stiffness and structural geometry. It is useful for analyzing beams, trusses, and frames, predicting reactions and internal forces, and understanding how structural members share loads under different loading conditions.

Flexibility Method - Related Videos

Research

JoVE Journal - Biology

An Efficient and Flexible Cell Aggregation Method for 3D Spheroid Production

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Cited by 67 •

2017

Here, we describe a rapid and flexible protocol for the formation of 3D cell spheroids through cell aggregation. This is easily adapted to multiple cell types and is suitable for use in a variety of applications including cell migration, invasion, or anoikis assays, and for imaging and quantifying cell-matrix interactions.

Research

JoVE Journal - Neuroscience

An Integrated Method for Crafting Flexible and Convenient Electrophysiological Optrodes for Multi-Region In Vivo Recording

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2024

We have developed a simplified and cost-effective approach for electrode fabrication and conducted recordings of signals across multiple regions in freely moving mice. Utilizing optogenetics, alongside multi-region electrophysiology and calcium signal recording, enabled the revelation of neuronal activities across regions in the seizure kindling model.

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation

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Cited by 1 •

2024

Presented here is a protocol for awake nasotracheal intubation using a flexible rhino-laryngoscope with a 300 mm working length. As this tool is minimally invasive and easy to manipulate, awake intubation performed with a flexible rhino-laryngoscope is well-tolerated, fast, and safe for patients with difficult airways.

Research

JoVE Journal - Behavior
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Operant Procedures for Assessing Behavioral Flexibility in Rats

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Cited by 68 •

2015

The ability to assess executive functions such as behavioral flexibility in rats is useful for investigating the neurobiology of cognition in both intact animals and disease models. Here we describe automated tasks for assessing strategy shifting and reversal learning, which are particularly sensitive to disruptions in prefrontal cortical networks.

Implantation of a Flexible Biocompatible Probe in a Glioblastoma Mouse Model

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2025

Source: Lefevre, M. C., et al., Flexible Organic Electronic Devices for Pulsed Electric Field Therapy of Glioblastoma. J. Vis. Exp. (2022)This video demonstrates the implantation of a flexible, biocompatible probe in a glioblastoma mouse model to deliver targeted pulsed electric field therapy for neurotherapeutic applications.

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