D2 Test

The D2 Test is a timed paper-and-pencil assessment of selective attention, concentration, and visual processing speed. It requires participants to scan rows of similar letters and symbols, identify target items according to specific rules, and mark them while avoiding distractors; performance reflects the accuracy and efficiency of sustained visual discrimination under time pressure. In behavioral research and psychological assessment, the test can help characterize attentional control, processing speed, and errors of omission or commission. Its standardized format supports comparisons across individuals and conditions, including studies of cognitive performance and attention-related changes.

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Research

JoVE Journal - Biochemistry

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools

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Cited by 1 •

2022

This protocol describes a comparative assay, using mitochondrial complex activities CI+CIII and CII+CIII in the presence or absence of Na+, to study the existence of partially segmented functional CoQ pools.

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

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Cited by 8 •

2016

Cognitive deficits are common in about one third of patients with amyotrophic lateral sclerosis, a neurological condition leading to progressive impairments in speech and movement abilities. To conduct cognitive tests in patients unable to speak or write a reliable and easy to administer eye-tracking paradigm was developed.

A Rabbit Aortic Valve Stenosis Model Induced by Direct Balloon Injury

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Cited by 2 •

2023

An appropriate animal model is needed to understand the pathologic mechanisms underlying aortic valve stenosis (AVS) and to evaluate the efficacy of therapeutic interventions. The present protocol describes a new procedure for developing the AVS rabbit model via a direct balloon injury in vivo.

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds

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2025

Plasmodium sexual development occurs in the mosquito midgut. Targeting the parasite's sexual stages is a promising strategy to block transmission. We developed Ookluc, a transgenic P. berghei expressing nanoluciferase after zygote formation, enabling high-throughput screening of transmission-blocking compounds. This article details the methods for screening using Ookluc.

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools

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Cited by 10 •

2020

Here, we present a protocol to use a curvelet transform-based, open-source MATLAB software tool for quantifying fibrillar collagen organization in the extracellular matrix of both normal and diseased tissues. This tool can be applied to images with collagen fibers or other types of line-like structures.

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