Biomedical Text Mining

Biomedical text mining is the computational analysis of scientific and clinical language to extract structured information from biomedical literature and related text sources. It uses natural language processing, including entity recognition, terminology normalization, relation extraction, and information retrieval, to identify concepts such as genes, proteins, metabolites, diseases, and interactions within unstructured documents. In biochemistry, these methods help researchers connect molecular entities with biochemical functions, pathways, experimental findings, and disease mechanisms across large bodies of research. Text mining can support hypothesis generation, evidence organization, and literature-based discovery while reducing the time required to locate relevant results and reveal relationships that may be difficult to detect manually.

Biomedical Text Mining - Related Videos

Research

JoVE Journal - Medicine
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Cloud-Based Phrase Mining and Analysis of User-Defined Phrase-Category Association in Biomedical Publications

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Cited by 9 •

2019

We present a protocol and associated programming code as well as metadata samples to support a cloud-based automated identification of phrases-category association representing unique concepts in user selected knowledge domain in biomedical literature. The phrase-category association quantified by this protocol can facilitate in depth analysis in the selected knowledge domain.

Research

JoVE Journal - Medicine
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Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

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Cited by 2 •

2025

This article describes RUGGED (Retrieval Under Graph-Guided Explainable disease Distinction), which integrates Large Language Model (LLM) inference with Retrieval-Augmented Generation (RAG). It draws evidence from expert-curated biomedical knowledge bases and peer-reviewed biomedical publications to synthesize new knowledge from up-to-date information, identify explainable and actionable predictions, and pinpoint promising directions for hypothesis-driven investigations.

Research

JoVE Journal - Biochemistry
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A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

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Cited by 2 •

2023

A computational protocol, CaseOLAP LIFT, and a use case are presented for investigating mitochondrial proteins and their associations with cardiovascular disease as described in biomedical reports. This protocol can be easily adapted to study user-selected cellular components and diseases.

Research

JoVE Journal - Medicine

Generation of Alginate Microspheres for Biomedical Applications

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Cited by 33 •

2012

In the following sections, we outline procedures for the preparation of alginate microspheres for use in biomedical applications. We specifically illustrate a technique for creating multilayered alginate microspheres for the dual purpose of cell and protein encapsulation as a potential treatment for type 1 diabetes.

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

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Cited by 4 •

2015

Two- and three-dimensional superhydrophobic polymeric materials are prepared by electrospinning or electrospraying biodegradable polymers blended with a lower surface energy polymer of similar composition.

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