Calcium Deficient Hydroxyapatite
Calcium Deficient Hydroxyapatite - Related Videos
05:41
Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
0 Views •
Cited by 19 •
2017
This paper describes a novel method for the rapid manufacture of high quality bioinspired nanoscale hydroxyapatite. This biomaterial is of great significance in the manufacture of a wide range of innovative medical devices for clinical applications in orthopedics, craniofacial surgery and dentistry.
07:14
Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
0 Views •
Cited by 4 •
2022
Novel nanocomposites of graphene nanoribbons and hydroxyapatite nanoparticles were prepared using solution-phase synthesis. These hybrids when employed in bioactive scaffolds can exhibit potential applications in tissue engineering and bone regeneration.
13:46
Separation of Single-stranded DNA, Double-stranded DNA and RNA from an Environmental Viral Community Using Hydroxyapatite Chromatography
0 Views •
Cited by 5 •
2011
We describe an efficient method to separate single-stranded DNA, double-stranded DNA and RNA molecules from environmental viral communities. Nucleic acids are fractionated using hydroxyapatite chromatography with increasing concentrations of phosphate-containing buffers. This method permits the isolation of all viral nucleic acid types from environmental samples.
05:21
Establishment of A Mouse Model of Aqueous Deficiency Dry Eye
0 Views •
Cited by 3 •
2024
Here, we present a method to establish a mouse model of aqueous-deficient dry eye by excising the extraorbital and infraorbital lacrimal glands and evaluate the changes in the ocular surface in aqueous deficiency dry eye.
01:30
Capital Deficiency in Liquidation: I
0 Views •
2026
During the liquidation of a partnership, a capital deficiency occurs when a partner’s capital account becomes negative after accounting for allocated losses and the payment of liabilities. Resolving such deficiencies is a critical step before the remaining assets can be distributed. However, complications arise when a partner is unable or unwilling to contribute additional funds to eliminate their deficiency.In cases where a partner cannot satisfy their capital deficiency, the loss must be...
FAQs
Calcium vacancies and substitutions involving phosphate or hydrogen phosphate alter the crystal lattice rather than simply reducing its calcium content. These structural changes increase the material’s solubility and surface reactivity relative to stoichiometric hydroxyapatite. As a result, the surface can participate more readily in ion exchange, dissolution, and reprecipitation when exposed to physiological environments.
Greater solubility allows Calcium Deficient Hydroxyapatite to undergo controlled mineral dissolution under physiological conditions. Dissolution can provide the chemical changes needed for subsequent apatite reprecipitation at the material surface. This behavior is important when a design requires mineral resorption together with formation of a surface layer that supports interaction between the implant or scaffold and surrounding bone.
The material can exchange ions with its surroundings, partially dissolve, and then support reprecipitation of apatite at its surface. This sequence links the crystal chemistry of the starting material to development of an apatite layer. In bioengineering, that surface transformation is relevant because it can contribute to bone integration for materials placed near bone tissue.
Compared with stoichiometric hydroxyapatite, Calcium Deficient Hydroxyapatite has a calcium-poor lattice with calcium vacancies and phosphate or hydrogen phosphate substitutions. Those features make it more soluble and surface-reactive. The distinction gives engineers a way to investigate materials with greater capacity for ion exchange, dissolution, and reprecipitation when controlled resorption is preferred.
Its combination of physiological reactivity and controlled mineral resorption supports investigation in several formats, including bone-graft substitutes, implant coatings, injectable cements, and tissue-engineering scaffolds. The appropriate format depends on the intended role of the material, such as providing a mineral surface, filling a site, or forming part of a scaffold designed for bone integration.
Ion exchange, dissolution, and reprecipitation can promote formation of an apatite layer on exposed material surfaces. For implant coatings, that transformation is relevant to the interface between the coating and bone. In bone-graft substitutes, the same surface behavior provides a basis for studying how mineral resorption and new apatite formation may support integration with surrounding tissue.
Evaluation should focus on whether the material shows the intended balance of surface reactivity, physiological dissolution, apatite-layer formation, and controlled mineral resorption. These outcomes connect directly to the proposed use of scaffolds or injectable cements, where the material must participate in a bone-related environment while supporting integration rather than remaining entirely unchanged.