Peakforce Qnm

PeakForce QNM is an atomic force microscopy mode that maps surface topography alongside local nanomechanical properties, including adhesion, deformation, and stiffness. It repeatedly brings a probe into brief contact with a sample, controls the maximum interaction force during each tap, and analyzes the resulting force-distance curves to generate quantitative property maps. In engineering, PeakForce QNM helps characterize polymers, composites, coatings, thin films, and other heterogeneous materials at nanoscale resolution. By correlating mechanical behavior with surface structure, the technique supports failure analysis, material development, quality control, and optimization of interfaces and advanced manufacturing processes.

Peakforce Qnm - Related Videos

Research

JoVE Journal - Chemistry

Au-Interaction of Slp1 Polymers and Monolayer from Lysinibacillus sphaericus JG-B53 - QCM-D, ICP-MS and AFM as Tools for Biomolecule-metal Studies

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Cited by 12 •

2016

To obtain basic information on the sorption and recycling of gold from aqueous systems the interaction of Au(III) and Au(0) nanoparticles on S-layer proteins were investigated. The sorption of protein polymers was investigated by ICP-MS and that of proteinaceous monolayers by QCM-D. Subsequent AFM enables the imaging of the nanostructures.

Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping

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Cited by 6 •

2014

A method for investigating the structure of a protein photoreceptor using atomic force microscopy (AFM) is described in this paper. PeakForce Quantitative Nanomechanical Property Mapping (PF-QNM) reveals intact protein dimers on a mica surface.

Research

JoVE Journal - Medicine
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In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface

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Cited by 1 •

2025

We establish a standardized in vitro model for studying cannabis vapor exposure at the air-liquid interface. This model provides a systematic approach to examine the impacts of vaporized cannabis, addressing the growing interest in cannabis vaporizers as an alternative to smoking.

Quartz-Crystal Microbalance Biosensor-Based Biopanning to Study Protein-Drug Interactions

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2025

This video demonstrates a method to study protein-drug interactions using QCM biosensor-based biopanning of the T7 phage-displayed peptide library. The biopanning of phages displaying a specific peptide on the QCM biosensor allows specific isolation of high-affinity peptides, followed by amino acid sequencing, which helps to identify specific interaction sites on the target protein.

Seedless Growth of Bismuth Nanowire Array via Vacuum Thermal Evaporation

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Cited by 1 •

2015

A protocol for seedless and high yield growth of bismuth nanowire arrays through vacuum thermal evaporation technique is presented.

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