Spatial Multiplexing

Spatial multiplexing is a communication technique that increases data capacity by transmitting multiple independent signals simultaneously through distinct spatial channels. In wireless systems, multiple-input multiple-output (MIMO) antennas use differences in signal paths, channel conditions, and receiver processing to separate these streams, while optical systems can encode data across separate fiber cores or propagation modes. This approach improves spectral efficiency without requiring additional bandwidth or higher transmission power, supporting high-speed cellular networks, wireless local-area networks, satellite links, and optical communications. Its performance depends on channel diversity, antenna or mode isolation, and accurate signal detection.

Spatial Multiplexing - Related Videos

Research

JoVE Journal - Bioengineering

Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles

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Cited by 8 •

2017

We demonstrate a microfluidic platform with an integrated surface electrode network that combines resistive pulse sensing (RPS) with code division multiple access (CDMA), to multiplex detection and sizing of particles in multiple microfluidic channels.

Research

JoVE Journal - Cancer Research
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Multiplex Immunohistochemical Analysis of the Spatial Immune Cell Landscape of the Tumor Microenvironment

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Cited by 7 •

2023

This protocol describes in detail how immune cell characterization of the tumor microenvironment using multiplex immunohistochemistry is carried out.

Multiplexed Barcoding Image Analysis for Immunoprofiling and Spatial Mapping Characterization in the Single-Cell Analysis of Paraffin Tissue Samples

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Cited by 4 •

2023

Multiplexed barcoding image analysis has recently improved the characterization of the tumor microenvironment, permitting comprehensive studies of cell composition, functional state, and cell-cell interactions. Herein, we describe a staining and imaging protocol using the barcoding of oligonucleotide-conjugated antibodies and cycle imaging, which allows for the use of a high-dimensional image analysis technique.

Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment

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Cited by 11 •

2023

In this article, a protocol for manual tyramide signal amplification (TSA) multiplex immunofluorescence (mIF) combined with image analysis and spatial analysis is described. This protocol can be used with formalin-fixed paraffin-embedded (FFPE) sections for the staining of two to six antigens per slide depending on the slide scanner available in the laboratory.

Spatial Molecular Imaging of the Glycome Using Mass Spectrometry

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Cited by 1 •

2025

This protocol details the key steps to enable rigorous and reproducible measurement of both glycogen and N-linked glycans using mass spectrometry imaging.

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