Isomeric State Detection

Isomeric state detection is the identification of metastable nuclear excited states, or nuclear isomers, that persist long enough to be distinguished from prompt nuclear decays. It works by measuring characteristic radiation from an isomeric transition, including gamma rays or internal-conversion electrons, and correlating their energies and arrival times with the state’s half-life. In nuclear physics, these measurements reveal excitation energies, spin-related decay behavior, and level lifetimes, helping researchers map nuclear structure and test models of electromagnetic transitions. The method also supports studies of reaction products and long-lived radioactive states.

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Research

JoVE Journal - Biology
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In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig

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Cited by 6 •

2021

The present protocol describes concise experimental details on the evaluation and interpretation of in vivo torque data obtained via electrical stimulation of the common peroneal nerve in anesthetized pigs.

Measurement of Maximum Isometric Force Generated by Permeabilized Skeletal Muscle Fibers

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Cited by 47 •

2015

Analysis of the contractile properties of chemically skinned, or permeabilized, skeletal muscle fibers offers a powerful means by which to assess muscle function at the level of the single muscle cell. In this article we outline a valid and reliable technique to prepare and test permeabilized skeletal muscle fibers in vitro.

Education

JoVE Core - Anatomy and Physiology

Isotonic and Isometric Muscle Contractions

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2024

Two primary types of muscle contractions are isotonic and isometric, each serving unique functions and involving distinct mechanisms. Both isotonic and isometric contractions are integral to the body's complex system of movement and stability. Isotonic exercises contribute significantly to functional strength and movement, while isometric contractions are crucial for maintaining posture and joint stability. Isotonic contractions Isotonic contractions occur when a muscle changes length while the...

Research

JoVE Journal - Biology
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Isometric and Eccentric Force Generation Assessment of Skeletal Muscles Isolated from Murine Models of Muscular Dystrophies

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Cited by 85 •

2013

Muscle function measurements contribute to the evaluation of potential therapeutics for muscle pathology, as well as to the determination of mechanisms underlying physiology of this tissue. We will demonstrate the preparation of the extensor digitorum longus and diaphragm muscles for functional testing. Protocols for isometric and eccentric contractions will be shown, as well as differences in results between dystrophic muscles, representing a pathological state, and wildtype muscles.

Isometric Contractility Measurement of the Mouse Mesenteric Artery Using Wire Myography

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Cited by 15 •

2018

The wire myograph technique is used to investigate vascular smooth muscle functions and screen new drugs. We report a detailed protocol for measuring the isometric contractility of the mouse mesenteric artery and for screening new relaxants of vascular smooth muscle.

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