Mechanical Tester
Mechanical Tester - Related Videos
11:38
Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization
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Cited by 9 •
2013
A method is discussed by which the in vivo mechanical behavior of stimuli-responsive materials is monitored as a function of time. Samples are tested ex vivo using a microtensile tester with environmental controls to simulate the physiological environment. This work further promotes understanding the in vivo behavior of our material.
09:45
Amplitude-Modulated Electrodeformation to Evaluate Mechanical Fatigue of Biological Cells
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Cited by 4 •
2023
Presented here is a protocol for mechanical fatigue testing in the case of human red blood cells using an amplitude-modulated electrodeformation approach. This general approach can be used to measure the systematic changes in morphological and biomechanical characteristics of biological cells in a suspension from cyclic deformation.
07:34
Layer Microdissection of Tricuspid Valve Leaflets for Biaxial Mechanical Characterization and Microstructural Quantification
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2022
This protocol describes the biaxial mechanical characterization, polarized spatial frequency domain imaging-based collagen quantification, and microdissection of tricuspid valve leaflets. The provided method elucidates how the leaflet layers contribute to the holistic leaflet behaviors.
12:45
Mechanical Stimulation of Chondrocyte-agarose Hydrogels
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Cited by 29 •
2012
The biosynthesis of cartilaginous extracellular matrix by chondrocytes can be affected by application of mechanical stimuli. This method describes the technique of applying dynamic compressive strains to chondrocytes encapsulated in 3D constructs and the evaluation of induced changes in chondrocyte metabolism.
03:06
Reaction Mechanisms
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2020
Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs. For instance, the decomposition of ozone appears to follow a mechanism with two steps:
FAQs
The instrument relates the applied force to the resulting displacement and uses the resulting stress-strain data to show how a specimen deforms. Elastic behavior describes deformation associated with the material’s load response, whereas failure marks the point at which structural integrity is no longer maintained. This distinction helps researchers assess strength, stiffness, and resilience.
Each loading mode examines response to a different type of mechanical demand. Tensile testing evaluates behavior under pulling, compression examines response to squeezing, and bending assesses deformation under flexural loading. Selecting among these modes allows bioengineers to study a tissue, scaffold, biomaterial, or prosthetic component under conditions that reflect the physical demands relevant to its intended use.
Stress-strain data provides a basis for comparing how materials or biological constructs respond as loading increases. The data can identify stiffness, strength, elastic behavior, deformation, failure, and resilience. Together, these outcomes show whether one design tolerates applied forces more effectively than another and whether its structural response is suitable for a targeted biological or medical application.
A typical workflow begins by selecting the material, tissue, or engineered construct and choosing tensile, compressive, or bending loading. The tester then applies a controlled load while recording force and displacement. Researchers use those measurements to generate stress-strain data, identify mechanical properties, and compare the specimen’s structural response with other designs or samples.
Loading conditions should correspond to the mechanical demands the tested material or construct is expected to experience. Researchers can select tensile, compressive, or bending tests according to the application, then examine the resulting force, displacement, and stress-strain behavior. This approach helps determine whether a scaffold, biomaterial, tissue, or prosthetic component can withstand relevant physical demands.
Mechanical testing is useful when researchers need evidence about the structural integrity of biomaterials, scaffolds, prosthetic components, or engineered tissues. Measurements support comparisons among designs and reveal whether a construct has appropriate strength, stiffness, deformation behavior, failure response, or resilience. These findings help determine whether the material is appropriate for a biological or medical application.