Circular Microchannels
Circular Microchannels - Related Videos
10:55
Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip
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Cited by 5 •
2013
A microchannels-on-a-chip platform was developed by the combination of photolithographic reflowable photoresist technique, soft lithography, and microfluidics. The endothelialized microchannels platform mimics the three-dimensional (3D) geometry of in vivo microvessels, runs under controlled continuous perfusion flow, allows for high-quality and real-time imaging and can be applied for microvascular research.
10:24
Preparation of 3D Collagen Gels and Microchannels for the Study of 3D Interactions In Vivo
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Cited by 16 •
2016
Collagen is a core component of the ECM, and provides essential cues for several cellular processes ranging from migration to differentiation and proliferation. Provided here is a protocol for embedding cells within 3D collagen hydrogels, and a more advanced technique for generating randomized or aligned collagen matrices using PDMS microchannels.
08:32
Assembly and Characterization of an External Driver for the Generation of Sub-Kilohertz Oscillatory Flow in Microchannels
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2022
The protocol demonstrates a convenient method to produce harmonic oscillatory flow from 10-1000 Hz in microchannels. This is performed by interfacing a computer-controlled speaker diaphragm to the microchannel in a modular manner.
08:39
Quantification of Circular RNAs Using Digital Droplet PCR
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Cited by 8 •
2022
This protocol describes the detailed method of digital droplet PCR (dd-PCR) for precise quantification of circular RNA (circRNA) levels in cells using divergent primers.
01:26
Circular Flow: Two Sector
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2025
An economy runs on the continuous movement of money, goods, and services between households and firms. The two-sector circular flow model focuses only on households and firms. It leaves out things like government, foreign trade, or banking to help us see the basic interactions more clearly. Households include individuals or families who earn income and use it to buy things they need. Firms are businesses that produce those goods and services using household resources. This creates a cycle where...
FAQs
In a circular microchannel, pressure drop, flow rate, and wall shear are linked through the channel geometry. This relationship gives engineers a basis for predicting how much pressure is needed to move a liquid or gas and how strongly the flowing fluid interacts with the walls. Such predictability supports controlled transport and design optimization in microscale systems.
As dimensions decrease, viscous effects and surface forces exert greater influence on fluid behavior. Engineers therefore must consider more than the intended flow path when designing a circular microchannel: the small scale changes how transport is controlled and how efficiently the device operates. These effects are especially relevant when managing flow, heat transfer, or mass transfer.
Their small scale allows circular microchannels to operate with small sample volumes and low energy inputs. Combined with predictable relationships among flow variables, this characteristic helps engineers design compact systems that control fluid movement without requiring large volumes or substantial energy resources. These advantages are relevant to microscale devices for transport, processing, analysis, and measurement.
Micromachining, molding, and additive manufacturing are identified routes for producing circular microchannels. These methods can create the channel structures required for fluid transport and allow engineers to incorporate them into microscale devices. Their use supports development across several engineering settings, including systems designed for cooling, chemical processing, biomedical analysis, and flow measurement.
These channels are useful when a device must transport or process fluids in a compact format. The overview identifies cooling, chemical processing, biomedical analysis, and flow measurement as application areas. Across these settings, their small dimensions can support low sample volumes and low energy inputs while their flow behavior provides a basis for controlling transport.
Engineers can use circular microchannels to optimize heat transfer and mass transfer while managing laminar flow. This makes the geometry relevant to systems where predictable fluid movement and efficient exchange are important. Studying the channels also helps connect microscale fluid behavior with practical device goals, including compact construction, controlled processing, and reduced sample and energy requirements.