Inter-particle Contact Evolution

Inter-particle contact evolution is the study of how contacts between individual particles form, change, and disappear over time, a process that controls the behavior of many particulate systems in engineering. Under applied loading or flow, particle motion, deformation, and rearrangement alter contact number, orientation, and transmitted forces, producing changing contact networks and load paths. Tracking this evolution helps explain macroscopic properties such as stiffness, strength, compaction, and flow, with applications in granular soils, powders, packed beds, and particulate composites. It also supports improved modeling of failure, transport, and processing in engineered materials.

Inter-particle Contact Evolution - Related Videos

Education

JoVE Core - Biology

The Evidence for Evolution

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2026

Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.The collection of fossils within sedimentary rocks give a record of common ancestry and often depicts the history of evolution.

Convergent Evolution

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2026

Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.The structures that arise from convergent evolution are called analogous structures. They are similar in function even if they are dissimilar in structure. Further, structures can be analogous while also...

Research

JoVE Journal - Biology

Molecular Evolution of the Tre Recombinase

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Cited by 4 •

2008

Here we report the generation of Tre recombinase through directed, molecular evolution. Tre recombinase recognizes a pre-defined target sequence within the LTR sequences of the HIV-1 provirus, resulting in the excision and eradication of the provirus from infected human cells. While still in its infancy, directed molecular evolution will allow the creation of custom enzymes that will serve as tools of molecular surgery and molecular medicine.

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

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Cited by 2 •

2022

Contact hypersensitivity (CHS) is a murine experimental model of allergic contact dermatitis (ACD). CHS is based on sensitization with reactive hapten by painting the shaved skin of the chest and abdomen, with a subsequent ear skin challenge with a diluted hapten, causing a swelling reaction that is assessed in various ways.

Research

JoVE Journal - Neuroscience

Inter-Brain Synchrony in Open-Ended Collaborative Learning: An fNIRS-Hyperscanning Study

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Cited by 7 •

2021

The protocol for conducting fNIRS hyperscanning experiments on collaborative learning dyads in a naturalistic learning environment is outlined. Further, a pipeline to analyze the Inter-Brain Synchrony (IBS) of oxygenated hemoglobin (Oxy-Hb) signals is presented.

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