Forelimb Grasp Reflex

The forelimb grasp reflex is an involuntary behavioral response in which tactile stimulation of the paw or palm triggers rapid flexion of the digits and forelimb to secure contact with an object. Sensory receptors detect pressure or touch and transmit signals through afferent nerves to spinal sensorimotor circuits, which activate motor neurons controlling flexor muscles; the response can be shaped by ongoing sensory feedback and brain input. Studying this reflex helps researchers assess sensorimotor development, neural circuitry, motor control, and recovery after nervous-system injury, while providing a measurable model for comparing innate behavior with learned grasping actions.

Forelimb Grasp Reflex - Related Videos

Research

JoVE Journal - Behavior

Neurodevelopmental Reflex Testing in Neonatal Rat Pups

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Cited by 74 •

2017

Behavioral testing is the gold standard for determining outcomes following brain injury, and can identify the presence of developmental disabilities in infants and children. Neurodevelopmental reflexes are an early indicator of these abnormalities. A host of easily accomplished developmental reflex tests in the neonatal rodent were developed and described here.

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

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Cited by 17 •

2015

A paradigm is presented to analyze the acquisition of a high-precision skilled forelimb reaching task in rats.

Research

JoVE Journal - Neuroscience
Free Sample

A Novel Method for Assessing Proximal and Distal Forelimb Function in the Rat: the Irvine, Beatties and Bresnahan (IBB) Forelimb Scale

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Cited by 55 •

2010

Here we will describe a rodent behavioral assay that can detect recovery of both proximal and distal forelimb function including digit movements during a naturally occurring behavior that does not require extensive training or deprivation to enhance motivation.

Research

JoVE Journal - Biology

Terminal H-reflex Measurements in Mice

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Cited by 3 •

2022

The clinical evaluation of spasticity based on the Hoffmann reflex (H-reflex) and using electrical stimulation of peripheral nerves is an established method. Here, we provide a protocol for a terminal and direct nerve stimulation for H-reflex quantification in the mouse forepaw.

Recording Forelimb Muscle Activity in Head-Fixed Mice with Chronically Implanted EMG Electrodes

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Cited by 2 •

2024

This protocol describes the hand fabrication and surgical implantation of electromyographic (EMG) electrodes in the forelimb muscles of mice to record muscle activity during head-fixed behavior experiments.

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