Timing Automation

Timing automation is the programmed control of when actions occur, allowing processes to run at defined intervals, in a specific sequence, or in response to measured conditions. In bioengineering, automated systems use clocks, timers, sensors, and control software to coordinate operations such as reagent addition, sampling, temperature changes, and instrument activation while reducing manual intervention. This approach improves reproducibility, supports precise multistep protocols, and helps maintain consistent experimental conditions. Timing automation is useful in bioprocessing, cell culture, diagnostic workflows, and laboratory instrumentation, where synchronized events can increase throughput, limit operator error, and enable reliable collection of time-dependent biological data.

Timing Automation - Related Videos

Research

JoVE Journal - Biochemistry

Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays

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Cited by 1 •

2016

Peptide adsorption to plasticware during traditional tip-based serial dilutions can significantly impact potency determination and confound the understanding of structure-activity relationships used for lead identification and lead optimization phases of drug discovery. Here methods for automated acoustic non-contact serial dilution of peptide samples are described.

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

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Cited by 2 •

2024

This protocol provides a method for tracking automated eye squint in rodents over time in a manner compatible with time-locking to neurophysiological measures. This protocol is expected to be useful to researchers studying mechanisms of pain disorders such as migraine.

Research

JoVE Journal - Environment
Free Sample

Reefshape: A System for the Efficient Collection and Automated Processing of Time-Series Underwater Photogrammetry Data for Benthic Habitat Monitoring

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Cited by 2 •

2025

Presented here is a protocol for collecting and processing underwater photogrammetry data, including a significantly simplified and fully automated image processing pipeline resulting in georeferenced and time-series aligned outputs ready for ecological data extraction, analysis, and application.

Research

JoVE Journal - Behavior
Free Sample

An Open-Source, Fully Customizable 5-Choice Serial Reaction Time Task Toolbox for Automated Behavioral Training of Rodents

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Cited by 1 •

2022

The present protocol describes the development of an open-source 5-choice serial reaction time task toolbox for rodent animal models, using Arduino and related hardware and a versatile Matlab toolbox, including an optional script for automated behavioral training. The scripts are customizable and facilitate the implementation of different trial-and-test designs.

An Automated Method to Determine the Performance of Drosophila in Response to Temperature Changes in Space and Time

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Cited by 4 •

2018

Here we present a protocol to automatically determine the locomotor performance of Drosophila at changing temperatures using a programmable temperature-controlled arena that produces fast and accurate temperature changes in time and space.

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