<p class="jove_content">The neuronal membrane proteasome (NMP) was recently identified in a subset of somatosensory neurons as a key regulator of touch, pain, and itch perception. This article presents a robust workflow for analyzing cell-type-specific NMP expression and function using cell sorting, transcriptome profiling, and culture-based immunofluorescent analyses.</p>

cell-subtype-specific-analysis-neuronal-membrane-proteasome

Cell Subtype-specific Analysis of Neuronal Membrane Proteasome in Somatosensory Neurons

Sensory neuron signaling depends on functional proteasomes, and their subcellular localization influences function. A specialized proteasome complex, the ...

Institution - Loyola University Chicago Stritch School of Medicine

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