<p class="jove_content">Prostate cancer heterogeneity and treatment resistance remain challenges. We describe a protocol for generating patient-derived organoids (PDOs) that preserve key parental tumor characteristics. This standardized model supports drug screening and precision medicine advancements. </p>

establishment-maintenance-patient-derived-prostate-cancer-organoids

Establishment and Maintenance of Patient-derived Prostate Cancer Organoids: A Detailed Experimental Protocol

Prostate cancer (PCa) is a highly heterogeneous malignancy and a leading cause of cancer-related mortality in men, with significant clinical challenges in ...

<p class="jove_content">This study presents an enhanced transperineal prostate biopsy technique using a cone-shaped double-hole method and dual-plane probe guidance. These modifications reduce trauma, enhance patient recovery, and improve biopsy accuracy, making the procedure a reliable and minimally invasive approach for prostate cancer diagnosis.</p>

transperineal-prostate-biopsy-using-cone-shaped-double-hole-method

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Prostate cancer, the second most common malignancy in men, frequently necessitates biopsy for accurate diagnosis. This study presents a transperineal ...

Institution - Jiangnan University Medical Center (Wuxi No. 2 People's Hospital)

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