<p class="jove_content">This protocol aims to test whether hydroxysafflor yellow A (HSYA) attenuates LPS-induced neurotoxicity in zebrafish. Motor function was evaluated using a Visual Vision system. Dopaminergic nerve injury was examined by immunohistochemistry. Molecules involved in the TLR4/NF-&#954;B pathway were analyzed using Western blot.</p>

hydroxysafflor-yellow-attenuates-lps-induced-toxicity-dopaminergic

Hydroxysafflor Yellow A Attenuates LPS-Induced Toxicity in Dopaminergic Neurons of Zebrafish by Regulating the TLR4/NF-&#312;B Signaling Pathway

Lipopolysaccharide (LPS)-induced inflammation plays a crucial role in triggering and perpetuating the neurodegenerative diseases, including Parkinson's ...

Institution - Yinfeng Biological Group Co., Ltd.

Articles Published in JoVE