This study demonstrates that adipose-derived stem cell-derived exosomes protect human melanocytes from H&#8322;O&#8322;-induced oxidative damage through activation of the Keap1&#8211;Nrf2&#8211;ARE pathway, supporting further investigation of their therapeutic potential for vitiligo.

amelioration-oxidative-stress-melanocytes-adipose-derived-stem-cell

Amelioration of Oxidative Stress in Melanocytes by Adipose-Derived Stem Cell Exosomes via the Keap1&#8211;Nrf2 Axis

Oxidative stress, particularly H&#8322;O&#8322; accumulation, is a key pathogenic factor in vitiligo, yet therapies that directly protect melanocytes ...

Here, we explore the impact of subcutaneous mastectomy under laparoscopy combined with in situ prosthetic breast reconstruction on breast cancer patients' aesthetic appearance. It details patient selection, preoperative preparation, surgical process, and postoperative outcomes. This approach effectively removes tumors while preserving breast shape, improving patients' self-esteem and quality of life.

impact-subcutaneous-mastectomy-under-laparoscopy-with-situ-prosthetic

Impact of Subcutaneous Mastectomy under Laparoscopy with In Situ Prosthetic Reconstruction on Aesthetic Appearance in Breast Cancer Patients

Breast cancer remains one of the most widespread malignant tumors affecting women, with a range of treatment options available, among which surgical ...

Institution - Wuzhong People's Hospital

Articles Published in JoVE