Hydroxyl Safflower Yellow A (HSYA) mitigates knee osteoarthritis by enhancing chondrocyte autophagy and proliferation while suppressing apoptosis and inflammation via HIF-1&#945;/BNIP3 pathway inhibition.

molecular-mechanism-hydroxyl-safflower-yellow-knee-osteoarthritis

Molecular Mechanism of Hydroxyl Safflower Yellow A in Knee Osteoarthritis through Modulation of Autophagy via Inhibition of the HIF-1&#945;/BNIP3 Pathway

The reduction of autophagy in cartilage tissue is closely linked to the development of knee osteoarthritis (KOA), yet the mechanisms by which Hydroxyl ...

Institution - Zhanjiang Central People's Hospital

Articles Published in JoVE