<p class="jove_content">In a prospective cohort of 200 patients with gastrointestinal stromal tumor (GIST) receiving first-line imatinib, a baseline five-metabolite plasma panel independently predicted progression-free survival. Internal validation showed improved discrimination and calibration over a clinical benchmark, supporting further external evaluation of the panel as a prognostic risk-stratification tool.</p>

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A 5-Metabolite Plasma Panel Predicts Progression-Free Survival and Adds Prognostic Value in Imatinib-Treated Gastrointestinal Stromal Tumors

Among patients with gastrointestinal stromal tumor receiving first-line imatinib, outcomes vary substantially, and traditional stratification based on ...

<p class="jove_content">Gonioscopy-assisted transluminal trabeculotomy significantly reduces intraocular pressure and medication in patients with primary open-angle glaucoma. Postoperative angle changes include forward iris insertion, narrowing angle width, pigment reduction and accumulation, and frequent PAS formation, predominantly in the nasal quadrant. These effects remain stable through the 12-month follow-up.</p>

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Institution - Chengdu First People's Hospital

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