This review examines the mechanisms and biomarkers of severe asthma to clarify their roles in guiding biologic treatment selection. It integrates established and emerging biomarkers with current biologic therapies and evolving precision strategies across type 2-high and type 2-low disease.

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Biologic Therapy for Severe Asthma: Biomarker-Guided Precision Treatment and Immunopathological Mechanisms

Severe asthma is a difficult-to-control airway disease with pronounced heterogeneity in both clinical manifestations and underlying inflammatory ...

This review highlights the growing potential of modern therapeutic approaches for the management of osteoarthritis (OA). Emerging strategies, including targeted molecular therapies, biologic agents, regenerative medicines, and lifestyle-based interventions, may help reduce inflammation, slow cartilage degeneration, and improve joint function. These advances could contribute to comprehensive long-term treatment strategies.

recent-advancements-management-osteoarthritis-an-updated

Recent Advancements in the Management of Osteoarthritis: An Updated Review

Osteoarthritis (OA) is a long-term progressive degenerative joint disorder that affects a substantial portion of the global population. It is primarily ...

This review synthesizes current evidence on 3D-printed porous titanium cages in lumbar interbody fusion, integrating material design principles, biomechanical performance, and clinical outcomes. Given increasing clinical adoption and heterogeneous reporting, a critical evaluation of existing data is timely and clinically relevant.

3d-printed-porous-titanium-cages-in-lumbar-interbody-fusion

3D-Printed Porous Titanium Cages in Lumbar Interbody Fusion

Lumbar degenerative disease is one of the most common indications for spinal surgery, and lumbar interbody fusion (LIF) remains a central technique in its ...

Institution - Zibo First Hospital

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