<p class="jove_content">This study aimed to develop and validate a rapid, sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of carfilzomib in human plasma. The fully validated method supports therapeutic drug monitoring in patients with multiple myeloma, thereby enabling personalized dose optimization.</p>

development-validation-rapid-lc-msms-method-for-carfilzomib

Development and Validation of a Rapid LC-MS/MS Method for Carfilzomib Quantification in Plasma from Multiple Myeloma Patients

Carfilzomib, a second-generation proteasome inhibitor, requires therapeutic drug monitoring (TDM). This study aimed to develop and validate a sensitive ...

Institution - Second Affiliated Hospital of Naval Medical University

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