Osthole (OST) is a natural compound with extensive pharmacological activities. This study suggests that OST alleviates the effects of Knee Osteoarthritis (KOA) via the miR-34a/Bcl-2 axis, as demonstrated in in vivo and in vitro studies in rats, and provides new ideas and directions for its patent medicine and clinical applications.

osthole-improves-rat-arthritis-through-the-mir-34abcl-2-axis

Institution - Shuyang Affiliated Hospital of Xuzhou Medical University

Articles Published in JoVE