<p class="jove_content">Integrated bioinformatics and experimental analyses identified LINC01871 as a potential predictor of cyclin-dependent kinase 4/6 inhibitor sensitivity and showed that LINC01871 overexpression suppresses breast cancer proliferation and is associated with reduced NF-&#954;B signaling.</p>

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LINC01871-Mediated Sensitivity to Cyclin-Dependent Kinase 4/6 Inhibitors in Human Breast Cancer

Breast cancer remains the most frequently diagnosed malignancy in women, and resistance to cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors limits ...

<p class="jove_content">This protocol describes a reproducible open-abdominal trans-caudal-artery chemoembolization technique in rats, enabling precise intra-arterial drug delivery, controlled liver embolization, and standardized assessment of therapeutic and biological responses in liver cancer models.</p>

transtail-artery-hepatic-artery-catheterization-rats-under-direct

Transtail Artery Hepatic Artery Catheterization In Rats Under Direct Vision: A Radiation-Free Method For Establishing Animal Models

Rat liver tumor models are indispensable for studying trans-arterial chemoembolization (TACE), drug delivery, and tumor biology. However, conventional ...

Institution - Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital

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