In spinal cord injury (SCI) patients, CASC11 upregulation is associated with injury severity. In vitro, CASC11 downregulation alleviated apoptosis and inflammation, suggesting an association with the miR-130b-5p/SPP1 axis. These results suggest CASC11&#8217;s potential role as a biomarker candidate&#160;in SCI pathogenesis.

association-serum-lncrna-casc11-with-injury-severity-inflammation

Association of Serum lncRNA CASC11 with Injury Severity and Inflammation in Spinal Cord Injury

Spinal cord injury (SCI) is a severe central nervous system trauma. This single-center, observational and in vitro study investigated the diagnostic ...

Institution - The Second People’s Hospital of Changzhi

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