<p class="jove_content">This protocol provides a standardized, high-throughput compound screening method using <em>in vivo</em> zebrafish to quantify dopaminergic neuron loss and locomotor behavioral deficits, enabling efficient screening of neuroprotective compounds.</p>

in-vivo-phenotyping-dopaminergic-neurodegeneration-zebrafish-larvae

In Vivo Phenotyping of Dopaminergic Neurodegeneration in Zebrafish Larvae Using Behavioral Analysis and High-Content Imaging

Drug discovery research in neurodegeneration is constrained by the high cost and low throughput of traditional mammalian models. This bottleneck is ...

Institution - UC Irvine School of Pharmacy and Pharmaceutical Sciences

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