This study established a novel in vivo beagle model of chronic moderate renal insufficiency combined with atrial fibrillation via transcatheter renal artery embolization and rapid atrial pacing, and demonstrated that this combination severely impaired left atrial endothelial function, enhanced procoagulant activity, and elevated thrombosis risk through inflammatory and RAAS-mediated pathways.

effects-chronic-renal-insufficiency-combined-with-atrial-fibrillation

Effects of Chronic Renal Insufficiency Combined with Atrial Fibrillation on Left Atrial Endothelial Function in a Beagle Model

The co-occurrence of atrial fibrillation (AF) and renal insufficiency (RI) represents a clinically complex phenomenon with high prevalence. This study ...

Institution - Subei People's Hospital of Yangzhou University

Articles Published in JoVE