<p class="jove_content">This protocol describes the establishment of an aggregated A&#946;1-42-induced Alzheimer&#8217;s disease-like mouse model and the assessment of triptolide effects on hippocampal inhibitory synapse-associated proteins, PI3K/Akt/GSK-3&#946; signaling, and autophagy-related markers.</p>

evaluating-triptolide-effects-on-hippocampal-gephyrin-collybistin

Evaluating Triptolide Effects on Hippocampal Gephyrin, Collybistin, and Autophagy in an A&#946;1-42 Mouse Model

Alzheimer&#8217;s disease is associated with synaptic dysfunction, but standardized procedures for evaluating how A&#946;-induced pathology affects ...

Institution - Southern University of Science and Technology Lansheng Brain Hospital / Sinopharm Dongfeng General Hospital Affiliated to Hubei University of Medicine

Articles Published in JoVE