<p class="jove_content">We conducted a systematic review and stage-stratified meta-analysis in which disease stage was prespecified as the principal effect modifier. The analysis found no significant pooled cognitive benefit across all disease stages, while early-stage trials showed directionally favorable cognitive, functional, and structural signals that require independent replication.</p>

stage-dependent-cognitive-effects-multinutrient-intervention

Stage-Dependent Cognitive Effects of a Multinutrient Intervention in Alzheimer&#39;s Disease: A Stage-Stratified Meta-Analysis

A specific multinutrient intervention provides precursors and cofactors for synaptic membrane synthesis. Randomized trials across the Alzheimer&#39;s ...

<p class="jove_content">This study investigated the interaction between FGD5-AS1 and miR-93-5p in experimental intracerebral hemorrhage models and found that FGD5-AS1 knockdown was associated with reduced neurological injury, inflammation, and oxidative stress.</p>

protective-effect-lncrna-fgd5-as1-against-brain-injury-after

Protective Effect of lncRNA FGD5-AS1 Against Brain Injury After Intracerebral Hemorrhage by Targeting miR-93-5p

Intracerebral hemorrhage (ICH) is a neurological disorder associated with high mortality and disability rates and can lead to severe neurological injury. ...

Institution - The Affiliated Hospital of Nanjing University Medical School

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