<p class="jove_content">This study employed network pharmacology and molecular dynamics simulations to investigate the molecular mechanisms and pathways of plumbagin in the treatment of prostate cancer. The results demonstrate that plumbagin may stably bind to AKT1, ESR1, BCL2, EGFR, TNF, MAPK3, HSP90AA1, SRC, and PPARG.</p>

computational-analysis-plumbagin-prostate-cancer-using-network

Computational Analysis of Plumbagin in Prostate Cancer Using Network Pharmacology and Molecular Dynamics Simulations

Prostate cancer is a major contributor to cancer-related mortality among men. Because many patients are diagnosed only after the disease has progressed to ...

Institution - Dongguan Key Laboratory of Medical Molecular Biology

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