<p class="jove_content">This study examines the piRNA-annotated small RNA hsa_piR_016984 in relation to TGF-&#946;1 mRNA stability and matrix staining in cultured human scleral fibroblasts exposed to cyclic stretch. The findings are limited to cellular responses under this defined loading regimen and do not establish mechanosensitivity as an intrinsic property of hsa_piR_016984.</p>

pirna-annotated-hsapir016984-regulates-extracellular-matrix

piRNA-Annotated hsa_piR_016984 Regulates Extracellular Matrix Homeostasis in Human Scleral Fibroblasts by Modulating TGF-&#946;1 mRNA Stability

Scleral extracellular matrix (ECM) remodeling is a pathological feature of axial myopia. The relationship between small-RNA-associated regulation and ...

<p class="jove_content">This chairside protocol delivers a biodegradable 14% doxycycline gel adjunctive to scaling and root planing for stage III/IV periodontitis, detailing screening, randomization, standardized instrumentation, gel placement with quality checks, follow-ups at 1, 3, and 6 months, and site-specific microbiological sampling with representative clinical and microbial outcomes.</p>

effect-local-14-doxycycline-gel-as-an-adjunct-to-scaling-root-planing

Effect of Local 14% Doxycycline Gel as an Adjunct to Scaling and Root Planing for Chronic Periodontitis: A Chairside Protocol with Representative Results

Adjunctive antimicrobials can enhance non-surgical periodontal therapy by suppressing residual pathogens within deep periodontal pockets. This article ...

Institution - Linhai Hospital of traditional Chinese medicine

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