<p class="jove_content">LIMCH1 regulates actin dynamics via NM-IIA binding, showing tumor-suppressive roles in lung/kidney/oral cancers but pro-oncogenic effects in breast/cervical cancers through alternative splicing, modifications, and networks, highlighting its prognostic and therapeutic potential in metastatic tumors.</p>

from-tumor-suppressor-to-tumor-promoter-dual-role-limch1-cancer-its

From Tumor Suppressor to Tumor Promoter &#8211; The Dual Role of LIMCH1 in Cancer and Its Clinical Implications

LIM and Calponin Homology Domain 1 (LIMCH1) is a multi-domain protein-coding gene located on human chromosome 4p13. Its encoded protein participates in ...

Institution - Jilin Medical University

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