This study integrates public pediatric pneumonia transcriptomics, mouse lung single-cell RNA sequencing, Paeonia-derived compound screening, molecular docking, and molecular dynamics simulations to identify neutrophil-associated inflammatory targets and predicted catechin interactions for future validation.

effects-paeonia-derived-catechin-on-neutrophil-associated

Effects of Paeonia-derived Catechin on Neutrophil-associated Inflammation in Pneumonia

Pneumonia in children is frequently accompanied by excessive inflammatory responses and immune dysregulation, which may lead to severe clinical outcomes. ...

Institution - Changchun Infectious Disease Hospital

Articles Published in JoVE