<p class="jove_content">Salvianolic acid B, a compound derived from Salvia miltiorrhiza, reduces cervical cancer cell viability, wound closure, proliferative activity, and epithelial-mesenchymal transition-associated molecular changes in HeLa and SiHa cells. Its actions are linked to the modulation of platelet glycoprotein Ib alpha and the downstream LYN kinase and TWIST1 transcription factor pathway.</p>

salvianolic-acid-b-suppresses-epithelial-mesenchymal-transition

Salvianolic Acid B Suppresses Epithelial-Mesenchymal Transition-Associated Phenotypes in Cervical Cancer Cells via GPIb Alpha/LYN/TWIST1 Signaling

Cervical cancer remains a major gynecological malignancy, and the epithelial-mesenchymal transition is associated with tumor progression. Salvianolic acid ...

Institution - Anhui Provincial Women and Children's Medical Center

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