<p class="jove_content">We identified VPA-related cryptorchidism reporting signals in male FAERS patients aged &#8804;18 years and used CTD, transcriptomic, and MR evidence to prioritize candidate genes rather than validate a mechanism. Of 108 broadly screened reports, 93 with transplacental/in utero exposure formed the exposure-focused subset for developmental interpretation.</p>

in-utero-valproic-acid-exposure-cryptorchidism-reports-integrating

In Utero Valproic Acid Exposure in Cryptorchidism Reports: Integrating FAERS, Toxicogenomics, Transcriptomics, and Mendelian Randomization

To screen the FDA Adverse Event Reporting System (FAERS) for valproic acid (VPA)-associated cryptorchidism reports, restrict developmental interpretation ...

Institution - The Affiliated Hospital of Chengde Medical University

Articles Published in JoVE