<p class="jove_content">This study integrates multiple public transcriptomic datasets to identify and prioritize prognostic and metastasis-associated biomarkers in prostate cancer and functionally evaluates the top candidate, myosin VI, in human prostate cancer cell lines using lentiviral knockdown, migration, invasion, proliferation, and Western blotting assays.</p>

multi-dataset-transcriptomic-screening-identifies-myosin-vi-as

Multi-Dataset Transcriptomic Screening Identifies Myosin VI as a Prognostic Biomarker Linked to Migration in Prostate Cancer

Distant metastasis remains a principal determinant of mortality in prostate cancer (PCa), yet markers associated with metastatic potential at an early ...

Institution - Dongfang Hospital, Beijing University of Chinese Medicine

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