<p class="jove_content">This protocol describes the stimulation of cultured fibroblasts with low-intensity pulsed ultrasound, which drives focal adhesion formation and Rac1 activation by mimicking engagement of the transmembrane matrix receptor, syndecan-4.  This approach allows investigation of a successful clinical technique at the cellular level, thereby providing opportunities for refinement of the therapy.</p>

induction-of-adhesion-dependent-signals-using-low-intensity-ultrasound

Institution - Smith and Nephew

Articles Published in JoVE