<p class="jove_content">The chromium release assay, a common assay for detecting cytotoxic T cell activity, has several limitations.  Using antigen-specific CD8 T cells and the human breast cancer tumor line, SKBR3, in the present article, an impedance-based approach was examined for the capability of detecting cell killing.</p>

determining-optimal-cytotoxic-activity-human-her2neu-specific-cd8-t

Determining Optimal Cytotoxic Activity of Human Her2neu Specific CD8 T cells by Comparing the Cr51 Release Assay to the xCELLigence System

Cytotoxic CD8 T cells constitute a subgroup of T  cells that are capable of inducing the death of infected or malignant host  cells1. These cells express ...

Institution - College of Medicine, Mayo Clinic

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