This protocol describes the development, expansion, and in vivo imaging of NK cells derived from hESCs and iPSCs.

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Development, Expansion, and In vivo Monitoring of Human NK Cells from Human Embryonic Stem Cells (hESCs) and Induced Pluripotent Stem Cells (iPSCs)

We present a method for deriving natural killer (NK) cells from undifferentiated hESCs and iPSCs using a feeder-free approach. This method gives rise to ...

A method of identifying unknown drivers of carcinogenesis using an unbiased approach is described. The method uses the Sleeping Beauty transposon as a random mutagen directed to specific tissues. Genomic mapping of transposon insertions that drive tumor formation identifies novel oncogenes and tumor suppressor genes

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Identification of Sleeping Beauty Transposon Insertions in Solid Tumors using Linker-mediated PCR

Genomic, proteomic, transcriptomic, and epigenomic analyses of human tumors indicate that there are thousands of anomalies within each cancer genome ...

Department of Obstetrics

Gynecology & Women's Health

Masonic Cancer Center

Department of Genetics

Cell Biology & Development

Center for Genome Engineering

Department of Medicine (Hematology

Oncology

and Transplant)

Stem Cell Institute

Department of Obstetrics, Gynecology & Women's Health, Masonic Cancer Center

Department of Genetics, Cell Biology & Development, Center for Genome Engineering

Department of Medicine (Hematology, Oncology, and Transplant)

University of Minnesota, Minneapolis

Institution - University of Minnesota, Minneapolis

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