Glioblastoma research involves challenges in the understanding of its progression and assessment of the tumor microenvironment. This protocol uses stereotaxic injection of brain cancer cells in mice to establish precise in vivo modeling of brain cancer, enabling detailed studies of tumor biology and therapeutic responses.

in-vivo-glioblastoma-tumor-modeling-via-stereotaxic-injection-mice

In Vivo Glioblastoma Tumor Modeling via Stereotaxic Injection in Mice for Tumor Progression Studies

Glioblastoma (GB) is a highly aggressive brain cancer with a median survival of under 2 years despite conventional therapy. Research efforts frequently ...

Here we describe a simple protocol for rapidly producing hundreds of nematode growth media agar, 96-well culture plates with consistent numbers of Caenorhhabditis elegans per well. These cultures are useful for the phenotypic screening of whole organisms. We focus here on using these cultures to screen chemicals for pro-longevity effects.

a-simple-method-for-high-throughput-chemical-screening-caenorhabditis

A Simple Method for High Throughput Chemical Screening in Caenorhabditis Elegans

Caenorhabditis elegans is a useful organism for testing chemical effects on physiology. Whole organism small molecule screens offer significant advantages ...

Institution - The Buck Institute for Research on Aging

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