<p class="jove_content">Optical coherence tomography (OCT), a three-dimensional imaging technology, was used to monitor and characterize the growth kinetics of multicellular tumor spheroids. Precise volumetric quantification of tumor spheroids using a voxel counting approach, and label-free dead tissue detection in the spheroids based on intrinsic optical attenuation contrast, were demonstrated.</p>

longitudinal-morphological-physiological-monitoring-three-dimensional

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Tumor spheroids have been developed as a three-dimensional (3D) cell culture model in cancer research and anti-cancer drug discovery. However, currently, ...

<p class="jove_content">Here, we demonstrate how image cytometry can be used for quantification of pathogenic fungi in association with host cells in culture.  This technique can be used as an alternative to CFU enumeration.</p>

use-image-cytometry-for-quantification-pathogenic-fungi-association

Institution - Nexcelom Bioscience LLC

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